Pathogenic Mechanisms of Bicuspid Aortic Valve Aortopathy
Bicuspid aortic valve (BAV) is Western spurs the most common congenital valvular defect and is associated with ascending aortic dilation (AAD) in a quarter of patients.AAD has been ascribed both to the hemodynamic consequences of normally functioning and abnormal BAV morphology, and to the effect of rare and common genetic variation upon function o